Med Star for Graduate Students Winners

November 2021
Andrew Locke
Nucleic Acids Research
SUMOylation mediates CtIP’s functions in DNA end resection and replication fork protection

July 2021
Adekunle Alabi
Nature Communications
Membrane type 1 matrix metalloproteinase promotes LDL receptor shedding and accelerates the development of artherosclerosis

March 2021
Hadeel Alyenbaawi
eLife
Seizures are a druggable mechanistic link between TBI and subsequent tauopathy

November 2020
Abul Azad
Oncogene
Inactivation of endothelial cell phosphoinositide 3-kinase β inhibits tumor angiogenesis
and tumor growth

July 2020
Cameron Griffiths
Nature
IGF1R is an entry receptor for respiratory syncytial virus

March 2020
Andrew Masoud
Journal of Clinical Investigation
Apelin directs endothelial cell differentiation and vascular repair following immune-mediated injury

November 2019
Brandon Hauer
eNeuro
The Reuniens Nucleus of the Thalamus Has an Essential Role in Coordinating Slow-Wave Activity between Neocortex and Hippocampus

July 2019
Amirali Bukhari
The Journal of Clinical Investigation
Inhibiting Wee1 and ATR kinases produces tumor-selective synthetic lethality and suppresses metastasis

March 2019
Bruno Saleme
Science Translational Medicine
Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity

November 2018
Mengcheng Shen
Circulation Research
Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic Aneurysm

July 2018
Brienne McKenzie
Proceedings of the National Academy of Science
Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis

March 2018 (tie)
Ruiqi Cai
Cell Reports
Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2

Andrew Woodman
FASEB Journal
Prenatal iron deficiency causes sex-dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver

November 2017
Dominic Golec
Journal of Experimental Medicine
Thymic progenitors of TCRαβ+ CD8αα intestinal intraepithelial lymphocytes require RasGRP1 for development

July 2017
Kyle Potts
EMBO Molecular Medicine
Deletion of F4L (ribonucleotide reductase) in vaccinia virus produces a selective oncolytic virus and promotes anti-tumor immunity with superior safety in bladder cancer models

March 2017
Richard Yan Do
Diabetes
A Glycine-insulin autocrine feedback loop enhances insulin secretion from Human β-Cells and is impaired in Type 2 Diabetes

November 2016
Tomas Gutierrez
Journal of Cell Biology
TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux

July 2016
Vrajesh Pandya
Oncotarget
The pro-apoptotic paradox: the BH3-only protein Bcl-2 interacting killer (BiK) is prognostic for unfavorable outcomes in breast cancer

March 2016
Azra Lari
Journal of Cell Biology
In vivo single-particle imaging of nuclear mRNA export in budding yeast domeonstrates an essential role for Mex67p

November 2015
Chengsheng Wu
BLOOD
STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma

July 2015
Devinderjit Kaur
The Journal of Cell Biology
A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores

March 2015
Ganesh Venkatraman
The FASEB Journal
Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: Implications for cancer treatment

November 2014
Daniel Unterweger
Nature Communications
The Vibrio cholerae type VI secretion system employs diverse effector modules for intraspecific competition

July 2014
Rajesh Alphonse
Circulation
Existence, Functional Impairment, and Lung Repair Potential of Endothelial Colony-Forming Cells in Oxygen-Induced Arrested Alveolar Growth

March 2014
Hai-feng Zhang
Carcinogenesis
miR-200b suppresses invasiveness and modulates the cytoskeletal and adhesive machinery in esophageal squamous cell carcinoma cells via targeting Kindlin-2

November 2013
David Van de Vosse
Cell
A Role for the Nucleoporin Nup170p in Chromatin Structure and Gene Silencing

July 2013
Ratnadeep Basu
Cardiovascular Research
TIMP3 is the primary TIMP to regulate agonistinduced vascular remodelling and hypertension

March 2013
Lucas Cairo
Molecular Cell, Vol 49, No. 109-120
Mitosis-Specific Regulation of Nuclear Transport by the Spindle Assembly Checkpoint Protein Mad1p

November 2012
Mahua Maulik
Human Molecular Genetics, Vol 21, No. 22
Mutant human APP exacerbates pathology in a mouse model of NPC and its reversal by a β-cyclodextrin

July 2012
Charlie Hsu
Biomaterials, Vol. 33, No. 31
A simple and rapid nonviral approach to efficiently transfect primary tissue-derived cells using polyethylenimine

March 2012
Alexander Suen
Proceedings of the National Academy of Sciences of the Unites States of America, Vol. 109, No. 3.
Proapoptotic protien Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens

November 2011
Vijay Kandalam
Circulation Research, Vol. 124, No. 19
Lack of Tissue Inhibitor of Metalloproteinases 2 Leads to Exacerbated Left Ventricular Dysfunction and Adverse Extracellular Matrix Remodeling in Response to Biomechanical Stress

July 2011
Emily Gesner
Nature Structural & Molecular Biology, Vol. 18, No. 6
Recognition and maturation of effector RNAs in a CRISPR interference pathway

March 2011
Mohammad Ali
Circulation, Vol. 122, No. 20
Titin is a Target of Matrix Matalloroteinase-2: Implication sof myocardinal ischemia/Reperfusion Injury

November 2010
Gopinath Sutendra
Science Transitional Medicine, Vol. 2, No. 44
Fatty Acid Oxidation and Malonyl-CoA Decarboxylase in the Vascular Remodeling of Pulmonary Hypertension

July 2010
Allison Kraus
Journal of Biological Chemistry, Vol. 285, No. 24
Calnexin Deficiency Leads to Dysmyeliation

March 2010
David Lesniak
American Association for Cancer Research, Vol. 69, No. 22
β1-Integrin Circumvents the Antiproliferative Effects of the Trastuzumab in Human Epidermal Growth Factor Receptor-2-positive Breast Cancer

December 2009
Jinlan (Jenny) Chang
Journal of Cell Biology Vol. 187, No. 2
Pex3 peroxsiome biogenesis proteins function in peroxisome inheritance as class V myosin receptors

September 2009
Cristina Ticu
The EMBO Journal, Vol. 28, No. 14
Conformational changes in switch I of EF-G drive its directional cycling on and off the ribosome

June 2009
Christian Rueda-Clausen
Cardiovascular Research , Vol. 81, No. 4
Effects of hypoxia-induced intrauterine growth restriction on cardiopulmonary structure and function during adulthood

December 2008
Andy Kokaji
Journal of Immunology, Vol. 180, No. 7
IL-15 transpresentation augments CD8+ T cell activation and is required for optimal recall responses by central memory CD8+ T cells

December 2008
Glen McDonald
Science, Vol. 322, No. 5903
Bioactive Contaminants Leach from Disposable Laboratory Plasticware