Maya Shmulevitz

Discovery

What Has a Nobel Prize Ever Done For You?

Turns out having all-star scientists on board draws students, researchers and funding that boost the economy

By Kate Black, ’16 BA

Turns out having all-star scientists on board draws students, researchers and funding that boost the economy

By Kate Black, ’16 BA

December 06, 2021 • 7 minute read

Leading researchers like Maya Shmulevitz, right, and Nobel laureate Michael Houghton enhance the reputation of the university, community and province.

A year ago, University of Alberta virologist Michael Houghton was one of three scientists to receive the Nobel Prize in Physiology or Medicine for his 1989 co-discovery of the hepatitis C virus.

The Nobel is as prestigious as prestige gets — an award that, by its own definition, recognizes contributions of the greatest benefit to humankind

For that moment, the U of A held the eyes of the world. But there’s much more to winning a Nobel Prize than bragging rights.

For one thing, the honour helps put the university on the map for prospective students and faculty, says Chris McCabe, executive director of the Edmonton-based Institute of Health Economics.

“The fact that we have a Nobel laureate makes the whole university more attractive,” says McCabe, who is also a U of A health economics professor. “The immediate impact is attracting the next generation of really bright and creative people to come here and do their research and develop ideas.”

This phenomenon isn’t limited to the Nobel Prize. Groundbreaking research begets more funding, and more funding begets groundbreaking researchers. If a U of A professor receives a grant from one of Canada’s three main funding bodies or is named a Canada Research Chair, for example, the resulting reputation and resources can attract sought-after talent to Alberta.

Houghton himself is an example of that. He was recruited to the U of A by Lorne Tyrrell, ’64 BSc, ’68 MD, a superstar in his own right for spearheading research that led to the development of the first oral treatment for hepatitis B. The university’s strong reputation in virology — and funding that included $10 million from the Canada Excellence Research Chair program — convinced Houghton to leave the private biotechnology industry in the U.S. in 2010 to work at the U of A. Now, he leads the university’s Li Ka Shing Applied Virology Institute.

Another example of that magnet effect came almost exactly a year after Houghton’s Nobel win. On Dec. 1, the province announced a $55.1-million grant for U of A research to prevent and treat COVID-19, including $15 million for vaccine projects and $10 million for studies on antiviral drugs. 

“If we’re going to remain competitive internationally — which we all want to be — you need great people with great instruments. This is critical,” said Tyrrell, who recently won the Hepatitis B Foundation’s highest honour for his pioneering research.

Connie Le, ’13 BSc, is one of the students who was attracted by the calibre of research at the university. As an MD/PhD student, she works alongside Tyrrell at the Li Ka Shing Institute of Virology to develop improved cell models to test potential cures for hepatitis B. She credits her early experiences with U of A research and Tyrrell’s support with her decision to stay in Edmonton for her studies.

In high school, Le had the opportunity to work in the lab of U of A surgery professor Gina Rayat, ’99 PhD. A couple of years later, Tyrrell guest-lectured one of Le’s undergraduate virology courses at the U of A. She was so inspired that she sent him an email introducing herself. Tyrrell encouraged her to pursue her MD/PhD, sparking a nearly decade-long mentorship.

“Dr. Tyrrell was gracious enough to meet with me. That discussion and seeing what a wonderful human he is was a huge part of why I decided to do a graduate degree with him,” Le says. 

“And now, having a Nobel laureate chatting with you in the hallway, that’s phenomenal. I’m so thankful these are the kind of experiences and opportunities afforded to me here.”

McCabe says students like Le who stay in the community contribute to the well-being of the province through a multiplier effect — the rippling economic impact of living and studying in the community. Graduate students, particularly, are likely to stick around and grow families and businesses in Edmonton, he says. 

The result is a city with a highly skilled labour force that contributes to the success of local businesses and startups and is a big sell for companies deciding where to locate. Having vibrant, healthy companies to work for keeps people living in the province and attracts more to come. 

“It’s a virtuous circle that can drive economic diversification,” McCabe says.

It also makes Alberta a magnet for top-quality research. 

One example is the international pharmaceutical companies that bring clinical trials to Alberta, says Lawrence Richer, ’92 BSc(Hons), ’96 MD, ’09 MSc, vice-dean of clinical research at the U of A’s Faculty of Medicine & Dentistry. These trials — which account for about 60 per cent of the province’s clinical trials — can contribute more than $100 million to Alberta’s economy in just one year, according to a 2018 study Richer helped conduct. 

Another 40 per cent of clinical trials in Alberta are initiated by researchers based in the province. Take Karen Madsen’s gut microbe transplant to reduce insulin sensitivity in obese patients, for example, or the CAR T-cell treatment for leukemia and lymphoma developed by Michael Chu, ’08 BMedSc, ’09 MD. In both cases, Edmonton-based patients have received potentially life-saving treatments because of the university’s presence in the city.

To attract and operate these trials, it’s essential to have high-calibre scientists and the teams of highly trained lab personnel, grad students and collaborators in other disciplines who support their work. 

“We don’t really have a big population and we’re not the cheapest place to do research. But what we do is of high quality,” says Richer, who is also director of the Northern Alberta Clinical Trials and Research Centre

“And the more we’re seen as a place to bring these treatments, the more the trials want to come here.”

What helps set the U of A apart is having people who are experienced in translating research from the lab bench to the patient’s bedside. That’s crucial for a strong health ecosystem. 

“That’s something we have that other institutions envy. It gives us an ability to do things that otherwise might not be possible,” Richer says. 

“You can have amazing ideas, great innovations and world-renowned research. But if it doesn’t somehow get implemented, if it doesn’t touch a patient, then what has it really done?”

Le, who is entering her fourth year of medical school while finishing her PhD thesis on hepatitis B, has studied and trained to do exactly that: take research results to patients and vice versa. 

“I like wearing those two hats,” she says. “As a clinician scientist, you can witness issues that occur with your patients and can use that as motivation and inspiration in the lab or through clinical research.”

Le was recognized in 2020 for her outstanding potential as a future leader and innovator in health care by the Canadian Medical Hall of Fame. Paired with the Vanier Canada Graduate Scholarship, she has received two of the most prestigious recognitions available to Canadian medical students and graduate students, respectively. 

It’s not hard to imagine the impressive career unfolding before her. But she’s hesitant to take credit without acknowledging the U of A scientists who helped set her on this path — Tyrrell and Houghton and a host of others: David Evans, ’78 BSc(Hons), ’82 PhD, James Smiley and Maya Shmulevitz, ’96 BSc(Hons), to name a few. 

“They’re wonderful examples of excellent scientists. They’re big shakers in the scientific community, but in doing so have impacted the local community here, too.”

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Karen Barnes Bolstered Education In the North
false
Alumni Awards
Howard Leeson Played a Key Role in Crafting Our Constitution
false
News
Restructuring Will Make UAlberta More Nimble, Efficient, Says President
false
Just For Fun
Wind Down the Year With Beer
false
Society
Three Paths
false
New Trail Classic
Do Not Bend or Mutilate — This Is a Human Being
false
Walking Together
Let’s Walk the Talk to End Racism
false
Discovery
An Inside Look at COVID-19 Research
false
Feature
The Future of Pandemics is Proactive
false
Living
'With This Hope We Can Do Beautiful Things'
false
Feature
Hope is an Overused Word, But the Real Thing Can be Powerful
false
At Home
A Common Quest
false
Living
Lawyers Get Creative As People Update Wills
false
Health
How to Neutralize Negative COVID-19 Thoughts
false
Living
Tips for Welcoming Refugees to Canada
false
At Home
Quarantine Bookshelf
false
Living
Six Things I’ve Learned About Embracing Discomfort
false
Thesis
Atypical Learning and Remarkable Results
false
DIY
Tuck Shop Cinnamon Bun Recipe
false
At Home
5 Books to Inspire Kids and Their Parents
false
Feature
A Justice for All
false
Thesis
Duplicate Studies
false
Thesis
Fair Play
false
Health
How I Learned to Ask for Help
false
Thesis
The Space Overhead
false
Tech
Inner Space
false
Energy
Indigenous Workers Tell Their Stories
false
Energy
People-Friendly Energy Projects
false
Energy
Powered Up
false
Energy
New Ways to Generate and Store Power
false
Did You Know
Meet Your New Alumni President
false
DIY
Build Your Own Robot From Junk at Home
false
Just For Fun
A Taste of Nostalgia
false
Health
How to Clean Your (Truly Gross, Germy) Phone
false
Money
How to Be Creative and Make Money
false
DIY
How to Make Your Words Last
false
DIY
How to Draw a Barn (on Fire)
false
Did You Know
How to Speak in Public With Aplomb
false
Tech
How Dylan Brenneis Built a Robot From Junk at Home
false
Living
Choose and Care for Your Perfect Christmas Tree
false
Health
Smoking Pot Behind Lister Is Legal
false
Thesis
How Long Until We Eat the Zoo?
false
Thesis
Have Your Burger and Eat It, Too
false
Alumni Awards
‘I think back with horror’
false
Trails
Tilting
false
Feature
Dementia Sets Lives Adrift. Research Is Finding a Better Way Forward
false
Health
The Elusive Cure
false
Thesis
Why You Feel Like Your Friends Are Having More Fun on Social Media
false
Thesis
Where Does Consciousness Live?
false
Living
Tips on How to Stink Less
false
Continuing Education
Five Things I’ve Learned About Perseverance
false
Continuing Education
Grant Me the Serenity to Accept My Inner Volcano
false
Tech
These Are Not Your Average Rabbits
These are not your average rabbits
false
At Work
How to Launch a Career During COVID-19
false
Profile
7 Things You Should Know About Billy-Ray Belcourt
false
Did You Know
What Do You Do When There’s No Reliable Internet?
false
Continuing Education
Check Your Blind Spots
false
Tech
They Saw What on YouTube?
false
Just For Fun
Flashback
Just For Fun
Fashion Sense
false
Discovery
Five Objects That Changed Our Lives
Alumni Awards
For giving Canadians insight into urgent global stories
false
Profile
For Fighting for LGBTQ Rights
Alumni Awards
For Bringing News and Entertainment to Canadian TV viewers
false
Feature
A Call to Bear Witness
false
Feature
Indigenous on Campus
false
Feature
Behind the Bodice
false
Feature
Reading Toward Reconciliation and More
News
Campus News
false
Did You Know
The Gateway's New Identity
false
Living
Put on Your Cape and Pants; It's Time to Go Out
false
Discovery
Research in the News
false
Continuing Education
Findings in the Field
false
Did You Know
Dark Cosmic Mysteries Illuminated
false
Environment
Alumni Among Wildfire Heroes
false
News
Research in the News
false
Discovery
'Welding' Neurons Opens Door to Repairing Nerves
false
Discovery
Paleontologists Discover Complete Baby Dino Skeleton
false
News
Alumni in the News
Did You Know
New Student Residence and Indigenous Gathering Place Coming to North Campus
false
Did You Know
Lecture Hall to Legislature
false
Health
When Food is Your Enemy
Discovery
Research Briefs
false
Environment
Our Man on Mars
false
Discovery
Who's the Boss of Evolution?
false
News
Kim Campbell Heads New College
Did You Know
From the Collections
false
Profile
Learning to Lead
false
Environment
Five Questions About Frankenstorms
false
Discovery
Blue Sky Green Moss
false
Profile
The Road to a Rhodes
News
Campus News
false
Health
A Mighty Heart
false
Did You Know
Medal of Freedom
false
Sweating the Small Stuff
false
Environment
Taking The Initiative
false
Discovery
Cell Mates
false
Did You Know
It Is Brain Surgery
false
In Memoriam
Remembering Robert Kroetch
Notes
Powerful Women
Notes
Royal Society of Canada Honours
Notes
Meet Your Reunion Organizer
false
Health
Treating the King Georges of Edmonton... and Calgary
false
Discovery
Weird Science
false
Feature
Whatsoever Things Are True
false
Feature
U of A's Newest Building
false
Continuing Education
Rhodes Worthy
false
Did You Know
Uphill Racer
false
Profile
PhD Prize Money