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Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury

The STARRT-AKI Investigators for the Canadian Critical Care Trials Group, the Australian and New Zealand Intensive Care Society Clinical Trials Group, the United Kingdom Critical Care Research Group, the Canadian Nephrology Trials Network, and the Irish Critical Care Trials Group*

July 16, 2020
N Engl J Med 2020; 383:240-251
DOI: 10.1056/NEJMoa2000741

CONCLUSIONS
Among critically ill patients with acute kidney injury, an accelerated renal-replacement strategy was not associated with a lower risk of death at 90 days than a standard strategy. (Funded by the Canadian Institutes of Health Research and others; STARRT-AKI ClinicalTrials.gov number, NCT02568722. opens in new tab.)