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Rylan Lundgren, PhD

Professor, Faculty of Science - Chemistry
Contact Overview Publications Links

Contact

Professor, Faculty of Science - Chemistry
Email
rlundgre@ualberta.ca
Phone
(780) 492-3766
Address
E4-17a Chemistry Centre - East
11227 Saskatchewan Drive NW
Edmonton AB
T6G 2G2

Overview

About

B.Sc. University of Manitoba

Ph.D. Dalhousie University

NSERC PDF Massachusetts Institute of Technology and California Institute of Technology


Research

Our research group is broadly interested in catalysis, organometallic chemistry, synthesis and reactivity. We seek to address problems and limitations in chemical synthesis by devising new concepts and tools related to homogeneous catalysis involving both transition metal and organic moieties. Specific interests include novel oxidative coupling reactions inspired by the reactivity of oxidase enzymes; simultaneous dual substrate activation strategies to enable, for example, olefin functionalizations; the development of new dehydrogenative processes; and alternative methods to generate single-electron reductants. Additionally, we are also interested in developing and exploiting strained unsaturated cyclic molecules as potential reagents for bioconjugation and click reactions.

Featured Publications

Enantio‐ and Z‐Selective δ‐Hydroarylation of Aryl‐Substituted 1,3‐Dienes via Rh‐Catalyzed Conjugate Addition

Hima Kozhummal, Sandip Kumar Das, Christopher J. C. Cooze, Rylan J. Lundgren

Angewandte Chemie International Edition. 2024 July; 10.1002/anie.202406102

Enantioselective Carbon Isotope Exchange

Michael G. J. Doyle, Odey Bsharat, Anna Sib, Volker Derdau, Rylan J. Lundgren

Journal of the American Chemical Society. 2024 July; 10.1021/jacs.4c03685

A practical guide for the preparation of C1-labeled α-amino acids using aldehyde catalysis with isotopically labeled CO2

Michael G. J. Doyle, Braeden A. Mair, Anna Sib, Odey Bsharat, Maxime Munch, Volker Derdau, Benjamin H. Rotstein, Rylan J. Lundgren

Nature Protocols. 2024 July; 10.1038/s41596-024-00974-4

Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2

Odey Bsharat, Michael G. J. Doyle, Maxime Munch, Braeden A. Mair, Christopher J. C. Cooze, Volker Derdau, Armin Bauer, Duanyang Kong, Benjamin H. Rotstein, Rylan J. Lundgren

Nature Chemistry. 2022 December; 10.1038/s41557-022-01074-0

Site‐Selective Hydrogenation of Electron‐Poor Alkenes and Dienes Enabled by a Rhodium‐Catalyzed Hydride Addition/Protonolysis Mechanism**

Duanyang Kong, Qiqige Qiqige, Wesley McNutt, Rocco Paciello, Ansgar Schäfer, Mathias Schelwies, Rylan J. Lundgren

Angewandte Chemie International Edition. 2022 October; 10.1002/anie.202210601

Diastereo-, Enantio-, and Z-Selective α,δ-Difunctionalization of Electron-Deficient Dienes Initiated by Rh-Catalyzed Conjugate Addition

Christopher J. C. Cooze, Wesley McNutt, Markus D. Schoetz, Bohdan Sosunovych, Svetlana Grigoryan, Rylan J. Lundgren

Journal of the American Chemical Society. 2021 July; 10.1021/jacs.1c05427

Fast Carbon Isotope Exchange of Carboxylic Acids Enabled by Organic Photoredox Catalysis

Duanyang Kong, Maxime Munch, Qiqige Qiqige, Christopher J. C. Cooze, Benjamin H. Rotstein, Rylan J. Lundgren

Journal of the American Chemical Society. 2021 February; 10.1021/jacs.0c12819

Direct reversible decarboxylation from stable organic acids in dimethylformamide solution

Duanyang Kong, Patrick J. Moon, Erica K. J. Lui, Odey Bsharat, Rylan J. Lundgren

Science. 2020 July; 10.1126/science.abb4129

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