Laboratory Medicine and Pathology Courses

Undergraduate

LABMP 400 Introduction to Human Disease
Lecture sessions on the study of human disease are presented. The causes and general mechanisms of disease with selected specific examples from various organ systems are discussed. Disease related structural and functional changes at the molecular, cellular and tissue level are presented, and how these changes can be appreciated by various laboratory methods. The discipline bridges basic science and clinical medicine.

Graduate

LABMP 500 Introduction to Human Disease
Lecture sessions on the study of human disease are presented (LABMP 400). The causes and general mechanisms of disease with selected specific examples from various organ systems are discussed. Disease related structural and functional changes at the molecular, cellular and tissue level are presented, and how these changes can be appreciated by various laboratory methods. A written review of scientific literature on a specific topic in Pathology will be required.

LABMP 510 Cryobiology I
Physiochemical changes in aqueous solutions at low temperatures and responses of living cells and tissues to those changes. Current theories of damage and protection during freezing and thawing. Prerequisite: consent of Department. This course may not be taken for credit if credit has already been received in PATH 510.

LABMP 511 Cryobiology II
Freeze-thaw responses of enzyme systems, individual cells and organized tissues. Preservation of spermatozoa, blood and bone marrow cells, embryos and various tissues. Approaches to the cryopreservation of organs and whole organisms. Applications in medicine and agriculture. Prerequisite: consent of Department. This course may not be taken for credit if credit has already been received in PATH 511.

LABMP 530 Experimental Design & Scientific Communication
This course is designed to develop the skills of graduate students in the areas of critical review of clinical and basic science literature, experimental study design, research ethics, concepts in oral and poster presentations of scientific research, abstract writing for clinical and basic science conferences, as well as how to maximize the scientific conference experience. Active class discussion is a component of each lecture, with group and individual assignments to give practical experiences to each student immediately applicable to their graduate research program. Open to graduate students and clinical residents in the Faculty of Medicine & Dentistry. Students from other faculties may register with consent of the instructors.

LAMBP 535 Practical Tools for Scientific Research
This course utilizes a workshop format designed to develop the skills of graduate students and clinical residents in scientific writing (i.e. literature reviews, manuscripts, grant applications), research budget planning, developing effective collaborations, intellectual property and technology transfer. An overview of the safety requirements (WHMIS, radiation safety, and biological hazards) in order to conduct scientific research. Students will learn how to prepare an ethics application for the use of animals and humans in research. Guest speakers from academia, government and industry are featured. Open to graduate students and clinical residents in the Faculty of Medicine & Dentistry. Students from other faculties may register with consent of the instructors.

LABMP 540 Directed Reading in Laboratory Medicine and Pathology
Reading and study of basic laboratory medicine and pathology topics relevant to the student's chosen field of study under the direction of one or more faculty members. Prerequisite: Consent of Graduate Co-ordinator, Laboratory Medicine and Pathology. LABMP 540 guidelines are followed.

LABMP 550 Analytical and Environmental Toxicology
Principles of and recent advances in analytical and environmental toxicology, fate and behaviour of environmental contaminants, sampling and analysis of toxic substances, biomonitoring and biomarkers.

LABMP 551 Laboratory Research Methods
Theory and practice of laboratory research techniques and methods. Fundamentals and applications of quantitative analysis, separation, atomic spectrometry, mass spectrometry, PCR and cloning with laboratory experiments. For students who will perform laboratory research.

LABMP 552 Toxicology and Regulation
This course will help students develop the understanding and skills to apply research results to real world needs for the management of risks posed by environmental contaminants as well as the development of regulation and policy involving such management. Open to graduate students in Laboratory Medicine and Pathology. Students from other departments may register with consent of the instructor.

LABMP 553 Advanced Environmental Toxicology
This course will focus on hazardous toxicant identification and assessment of effects. It will examine exposure and effects of toxicants on a number of different levels including a) molecular effects, b) tissue effects, c) individual and organismal effects, and d) population effects. Case studies will be used to illustrate different applications and the utilization of specific approaches to hazard identification and assessment. The concept of Adverse Outcome Pathways (AOPs) will be introduced and students will be responsible for developing their own AOP for a specific toxicity.

LABMP 581 Techniques in Molecular Biology
A laboratory course emphasizing introductory and advanced techniques in molecular biology (MLSCI 481). Isolation of RNA, Northern blotting, construction of cDNA, amplification of DNA by the polymerase chain reaction, analysis of DNA by restriction digestion, transfection of eukaryotic cells for protein expression and Western blotting analysis. Prerequisites Genetics and BIOCHEM 200 and BIOCH 330 and consent of the Department. A written review of scientific literature on a topic in molecular biology will be required. This course is designed for graduate students. Credit may only be obtained in one of MLSCI 481 or LABMP 581.

LABMP 590 Technology and the Future of Medicine
A lecture and seminar course describing the future effects of technology on medicine in both the developed and developing world, the promise and perils of biotech, nanotech, and artificial intelligence, and changing character of research and practice of medicine and pathology in the coming decades, and the technologic singularity. Each student will carry out a project supervised by a faculty member and give a presentation. This course is designed for graduate students in the Faculties of Medicine, Science, or Arts, and is open to undergraduates in those Faculties with consent of Department.

LABMP 593 Systemic Pathology
This course will provide an in-depth review of body organ systems and disease through lectures and seminars. This course is designed primarily for students enrolled in the Pathologists' Assistant specialization.

LABMP 594 Anatomic Pathology Techniques
This course will provide an introduction to the role of the Pathologists' Assistant in the clinical laboratory and principles of techniques used in the anatomic pathology laboratory, along with interactive demonstrations. Topics will include laboratory safety, review of specimen types encountered in the laboratory, specimen handling, submission of tissue and material for ancillary studies, gross description and dissection techniques, autopsy techniques, and photography. This course is designed primarily for students enrolled in the Pathologists' Assistant specialization.

LABMP 595 Laboratory Management
This seminar course offers topics for consideration in the administration of the clinical laboratory. Topics include finance, organizational behaviour, change management, human resource management, collective agreements, safety, risk management, ethics, the Health Professions Act, equipment acquisition, contracts, accreditation, and materials management. This course is designed primarily for students enrolled in the Pathologists' Assistant specialization.

LABMP 596 Pathologists' Assistant Clinical Practicum I
As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in laboratory medicine that include clinical biochemistry, clinical hematology & transfusion medicine, clinical microbiology, and clinical histology, as well as rotations in the pathology laboratories that include autopsy, surgical pathology, pediatric pathology and forensic pathology. The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

LABMP 597 Pathologists' Assistant Clinical Practicum II
As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in autopsy, surgical pathology, pediatric pathology and forensic pathology. The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

LABMP 598 Pathologists' Assistant Clinical Practicum III
As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in autopsy, surgical pathology, pediatric pathology and forensic pathology. The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

LABMP 599 Pathologists' Assistant Clinical Practicum IV
As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in autopsy, surgical pathology, pediatric pathology and forensic pathology (and additional community-based experiences, as available). The student will be expected to cover specific competencies and objectives, and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

LABMP 900 Research Project
The course is an independent research project supervised by a pathologist, pathologist's assistant or researcher. The student will choose the advisor and research project. The advisor will provide mentorship for the project. Seminar sessions cover topics relevant to conducting independent scientific research. The student will be expected to write a research proposal, keep an accurate laboratory notebook, and conduct adequate experimental research. The project will be written as a research paper and presented at departmental rounds.