Archive

Projects

  • Impact of Body Habitus on Cup Alignment in Total Hip Arthroplasty (THA) (2015)
    During THA, alignment of surgical implants is critical to lead to a good patient outcome. Patients are positioned on their side to optimize the surgeon's view of their hip joint. Patients with large differences in hip to shoulder ratios (i.e. narrow shoulders with broad hips or broad shoulders with narrow hips) may experience a pelvic tilt leading to mal-placement of the THA cup. Subjects waiting for THA were examined with a single low dose CT scan performed in a side-lying position to determine if shoulder to hip ratio affects pelvic positioning and alignment. These data were modelled using a software program to determine if there is a critical ratio beyond which a different surgical reference point is required. These data are currently under analysis. This work was supported by the ECE Charitable Foundation.
  • Infection Resolution and Function using the PROSTALAC Hip System (2015)
    Periprosthetic joint infection (PPJI) is a significant complication following total hip arthroplasty and the PROSTALAC THA assists in resolving infection while retaining the soft tissue space and allowing patients reasonable function. We evaluated health-related quality of life (HRQL) with the PROSTALAC in situ for infected total hip arthroplasty (THA), determined infection resolution, and compared subjects who underwent second stage surgery with those who retained the PROSTALAC on a longer term basis. Twenty-five of 29 (86%) subjects' infections resolved. After PROSTALAC insertion, pain and function improved within 3-6 months and was retained at 24 months. 7/22 (32%) subjects underwent second stage surgery. They were higher physical demand subjects than those not undergoing second stage surgery. We found no difference in WOMAC scores at 24 months between those who underwent second stage surgery and those who retained the PROSTALAC. The PROSTALAC system for THA appears to allow acceptable HRQL while in situ for at least 2 years in low physical demand patients. Subjects with higher physical demand levels are more likely to undergo second stage surgery. This work was supported by an unrestricted research grant from DePuy INC and the Edmonton Orthopaedic Research Committee. These results have been published in the Journal of Orthopaedic Surgery.
  • Ceramic on Ceramic (CoC) Bearing versus Ceramic on Crossfire® Highly Cross-Linked Polyethylene (CoP) Bearing in Primary Total Hip Arthroplasty: A Randomized Controlled Trial (2014)
    This trial compared functional outcomes and implant longevity between subjects who received either the CoC or CoP bearing surface at 5 and 10 years postoperatively. All subjects were 60 years old or younger on entrance to the trial. We found no group differences in function or longevity related to bearing surfaces at 5 or 10 years postoperatively. This work was supported by the Edmonton Orthopaedic Research Committee. The 5-year and 10-year results were published in the Journal of Arthroplasty.
  • A Randomized Clinical Trial of Posterior Cruciate Stabilizing (PCS) versus Posterior Cruciate Retaining (PCR) Prostheses in Primary Total Knee Arthroplasty (TKA) (2014)
    This trial compared functional outcomes and implant longevity between subjects who received either a PCS or PCR TKA at 2 and 10 years postoperatively. We found no group differences in function or longevity related to implant design at 2 or 10 years postoperatively. This work was supported by the Edmonton Orthopaedic Research Committee. The 2-year results were published in the Journal of Bone and Joint Surgery (American) and the 10-year results were published in the Journal of Arthroplasty.
  • Impact of Total Knee Arthroplasty (TKA) on Bone Mineral Density (BMD) (2003)
    We examined the changes in hip and spine BMD over the first year after primary TKA in 100 subjects (67 females; 33 males). We found that hip BMD changed more than that expected with age over the first year, particularly in older men and younger women. The study was supported by the University Hospital Foundation and Alberta Arthroplasty Research Group. This work was published in the Journal of Arthroplasty.

Grants

Pre-Operative Rehabilitation Exercise Program for Total Knee Arthroplasty (PREP).
Principal Investigators:  CA Jones
Funder: Canadian Institute of Health Research Establishment Grant; Alberta Heritage Foundation for Medical Research Establishment Grant.
Term:  Jul 2007-Jun 2014

Infection Resolution and Function using the PROSTALAC Hip System
Principal Investigtor: G. Lavoie
Funder: Edmonton Orthopaedic Research Committee Research Grant; DePuy/J&J INC.
Unsrestricted Research Grant
Term: Jan 2004-Dec 2015

Impact of Total Knee Replacement on Bone Mineral Density Principal Investigator(s): SR Majumdar, LA Beaupre, M Clark
Funder: University Hospital Foundation, Alberta Arthroplasty Research Group Research Grant
Term: Jan 2010 -Dec 2012

Grants Awarded in the last five years on which a team member was a co-applicant:

Alberta Innovatives-Health Solutions (AIHS) Creating Bone and Joint Health from the Bedside to the Bench and Back Again - "Designer Therapies" to Reduce the Burden of Osteoarthritis (OA) - from Mechanisms to Prevention
Co-Principal Investigators: CR Frank, W Herzog
Funder: Alberta Heritage Foundation for Medical Research Team Grant
Term: May 2008-Dec 2014

 Publications 

  • Herman B, Litchfield R, Getgood (2015). A. Role of osteotomy in posterolateral instability of the knee. Journal of Knee Surgery, 28(6):441-9.
  • Jones CA, Westby MD. (2015). Effect of non-surgical, non-pharmacological weight loss interventions in patients who are obese prior to hip and knee arthroplasty surgery: A rapid review. Systematic Reviews, 27(4):121. http://dx.doi.org/10.1186/s13643-015-0107-2
  • Beaupre LA, Rezansoff AJ (co-1st author), Clark M, Jen H, Lambert R, Majumdar SR. (2015). Bone mineral density changes in the hip and spine of men and women 1-year after Primary Cemented Total Knee Arthroplasty: Prospective cohort study. J Arthroplasty, 30(12):2185-2189. http://dx.doi.org/10.1016/j.arth.2015.06.026
  • Barnabe C, Hemmelgarn B, Jones CA, Peschken CA, Voaklander D, Joseph L, Bernatsky S, Esdaile J, Marshall D. (2015). Imbalance of prevalence and specialty care for osteoarthritis for First Nations People in Canada. J Rheumatol, 42(2):323-328 http://dx.doi.org/10.3899/jrheum.140551
  • Amusat N, Beaupre LA, Warren S, Simpson S, Jones CA. (2014). Diabetes that impacts on routine activities predicts slower recovery after total knee arthroplasty: An observational study. J of Physiother, 60(4):217-223. http://dx.doi.org/10.1016/j.jphys.2014.09.006
  • Beaupre LA, Masson ECO, Luckhurst BJ, Arafah O, O'Connor GJ. (2014). A randomized pilot study of an intensive postoperative exercise program compared with usual care following primary total hip arthroplasty in subjects less than 65 years of age: Feasibility, selection of outcome measures and timing of assessment. BMC Musculoskel Dis, 15:192. http://dx.doi.org/10.1186/1471-2474-15-192
  • Powell PJ on behalf of the Canadian Arthroplasty Society. (2013). The Canadian Arthroplasty Society's experience with hip resurfacing arthroplasty: An analysis of 2773 hips. Bone Joint J, 95-B:1040-1044.
  • Beaupre LA, Manolescu A, Johnston DWC. (2013). Five-year outcome of ceramic on ceramic bearing versus ceramic on Crossfire® highly cross-linked polyethylene bearing in primary total hip arthroplasty: A randomized trial of 92 subjects 60 years of age or younger. J Arthroplasty, 28:485-489.
  • Alhaideb A, Muir SW, Huckell J, Alsaleh KA, Johnson MA, Johnston DWC, Beaupre LA. (2013). Inter-observer reliability of the radiographic assessment of cement fixation in total hip arthroplasty. Eur J Orthop Surg Traum, 23(8):889-894. Article first published online: 2012, October 18. http://dx.doi.org/10.1007/s00590-012-1108-7
  • Gooch K, Marshall D, Smith D, Faris P, Khong H, Wasylak T, Pearce T, Johnston B, Arnett G, Parker R, Hibbert J, Beaupre L, Zernicke R, Frank C. (2012). The comparative effectiveness of a new evidence based clinical pathway versus the standard of care for primary hip and knee joint replacements. Osteoarthrit Carti, 20(10):1086-94.
  • Beaupre LA, Secretan C, Johnston DWC, Lavoie GJG. (2012). A randomized controlled trial comparing patellar retention versus patellar resurfacing in primary total knee arthroplasty: 5-10 year follow-up. BMC Res Notes, 5:273. http://dx.doi.org/10.1186/1756-0500-5-273
  • MacKenzie J, O'Connor G, Pettit P, Marshall DA, Faris PD, Dort L, Khong H, Werle J, Powell J, Beaupre L, Frank C, on behalf of the Alberta Hip Improvement Project (HIP) Advisory Committee and the Alberta Arthroplasty Research Group (AARG). (2012). Functional outcomes over 2 years comparing hip resurfacing and total hip replacement. The Alberta HIP Study. J Arthroplasty, 27(5):750-57. e2 http:/dx.doi.org/10.1016/j.arth.2011.10.004
  • Beaupre LA, Johnston DWC, Dieleman S, Tsui B. (2012). Pre-emptive multi-modal analgesia with or without femoral nerve blockade following primary total knee arthroplasty: A controlled clinical pilot study. TSW J, vol. 2012, Article ID 273821, 6 pages. http://dx.doi.org/10.1100/2012/273821
  • Jones CA, Pohar S. (2012). Health-related quality of life after total joint arthroplasties: A scoping review. Clinic Geriatr Med, 28(3):395-429.
  • Jones CA, Cox V, Jhangri GS, Suarez-Almazor ME. (2012). Delineating the impact of obesity and its relationship on recovery after total joint arthroplasties Osteoarthr Cartil, 20:511-518.
  • Davis AM, Cott C, Landry MD, Li L, Jones A, Lineker S, Mackay C, Muzzatti A, Venkataramanan V, Wong R. (2010). Care for people with arthritis: Policy: Decisions, impacts, and gaps. Arthritis Community Research and Evaluation Unit (ACREU), Report Number: MOCA2010-07/005. http://www.modelsofcare.ca/pdf/10-05.pdf
  • Gooch KL, Smith D, Wasylak T, Faris PD, Marshall DA, Khong H, Hibbert JE, Parker RD, Zernicke RF, Beaupre L, Pearce T, Johnston DW, Frank C. (2009). The Alberta Hip and Knee Replacement Project: A Model for health technology assessment based on comparative effectiveness of clinical pathways. Int J Technol Assess Health Care, 25(2):113-23.http://dx.doi.org/10.1017/S0266462309090163

  • Chaudhary R, Beaupre LA, Johnston DWC. (2008). Knee range of motion over the first two years using posterior cruciate stabilizing or posterior cruciate retaining prostheses in primary total knee arthroplasty: A randomized clinical trial. J Bone Joint Surg, 90A:2579-2586.

  • Beaupre LA, al-Yamani M, Huckell JR, Johnston DW. (2007). Hydroxylapatite coated tibial implants compared with cemented tibial fixation in primary total knee arthroplasty. A randomized trial of outcomes at five years. J Bone Joint Surg, 89A:2204-11

  • Jones CA, Beaupre LA, Johnston DW, Suarez-Almazor ME. (2007). Total joint arthroplasties: Current concepts of patient outcomes after surgery. Rheum Dis Clin North Am, 33(1):71-86. http://dx.doi.org/10.1016/j.rdc.2006.12.008c

  • Scharfenberger A, Clark M, Lavoie G, O'Connor G, Masson E, Beaupre LA. (2007). Treatment of an infected total hip replacement with the PROSTALAC system Part 1: Infection resolution. Can J Surg, 50:24-28.

  • Scharfenberger A, Clark M, Lavoie G, O'Connor G, Masson E, Beaupre LA. (2007). Treatment of an infected total hip replacement utilizing the PROSTALAC system Part 2: Health-related quality of life and function with the PROSTALAC implant in situ. Can J Surg, 50:29-33.

  • Jones CA, Beaupre LA, Johnston DW, Suarez-Almazor ME. (2005). Total joint arthroplasties: Current concepts of patient outcomes after surgery. Clin Geriatr Med, 21:527-41. http://dx.doi.org/10.1016/j.cger.2005.02.005

  • Beaupre LA, Lier D, Davies, DM, Johnston DB. (2004). The effect of a preoperative exercise and education program on functional recovery, health-related quality of life and health service utilization following primary total knee arthroplasty. J Rheumatol, 31:1166-73.

  • Roorda LD, Jones CA, Waltz M, Lankhorst GJ, Bouter LM, van der Eijken JW, Willems WJ, Heyligers IC, Voaklander DC, Kelly KD, Suarez-Almazor ME. (2004). Satisfactory cross-cultural equivalence of the Dutch WOMAC osteoarthritis index in patients with osteoarthritis waiting for arthroplasty. Annals of the Rheumatic Diseases, 63:36-42.
  • Rivard A, Warren S, Voaklander D, Jones A. (2003). The efficacy of pre-operative home visits for total hip replacement clients. Canadian Journal of Occupational Therapy, 70(4):226-232.
  • Jones CA, Voaklander DC, Suarez-Almazor ME. (2003). Determinants of function after total knee arthroplasty. Phys Ther, 83(8):696-706.

  • Davies DM, Johnston DW, Beaupre LA, Lier DA. (2003). Effect of adjunctive range-of-motion therapy after total knee arthroplasty on the use of health services after hospital discharge. Can J Surg, 46:30-6

  • Harley BJ, Beaupre LA, Jones CA, Cinats JG, Guenther CR. (2002). The effect of epsilon amicaproic acid on blood loss in patients who undergo primary total hip replacement: A pilot study. Can J Surg, 45:185-90.

  • Johnston DW, Davies DM, Beaupre LA, Lavoie G. (2001). Standard anatomical medullary locking (AML) versus tricalcium phosphate-coated AML femoral prostheses. Can J Surg, 44:421-7.

  • Beaupre LA, Davies DM, Jones CA, Cinats JG. (2001). Exercise combined with continuous passive motion or slider board therapy compared with exercise only: A randomized controlled trial of patients following total knee arthroplasty. Phys Ther, 81:1029-1037

  • Jones CA, Voaklander DC, Johnston DWC, Suarez-Almazor ME. (2001). The effect of age on pain, function and quality of life after total hip and knee arthroplasties. Arch Int Med, 161(3):454-460.

  • Jones CA, Voaklander D, Johnston DWC, Suarez-Almazor ME. (2000). Health-related quality of life outcomes after total hip and knee arthroplasties in a community-based cohort. J Rheumatol, 27:1745-1752.

  • Johnston DW, Beaupre LA, Davies DM, Hessels R. (1999). Reducing arthroplasty costs via vendor contracts. Can J Surg, 42:445-49.
  • Cott CA, Davis AM, Badley EM, Wong R, Canizares M, Li LC, Jones A, Brooks S, Ahlwalia V, Jaglal S, Hawker G, Landry MD, McKay C, Mosher D. (2016). Commonalities and differences in the implementation of models of care for arthritis: key informant interviews from Canada, BMC Health Services Research, 16(1):415. http://dx.doi.org/10.1186/s12913-016-1634-9
  • Herman B, Litchfield R, Getgood A. Role of osteotomy in posterolateral instability of the knee. Journal of Knee Surgery (2015); 28(6): 441-9.
  • Lui M, Jones CA, Westby MD. (2015). Effect of non-surgical, non-pharmacological weight loss interventions in patients who are obese prior to hip and knee arthroplasty surgery: A rapid review. Systematic Reviews, 27(4):121. http://dx.doi.org/10.1186/s13643-015-0107-2

  • Abstracts

    • Jasper L, Jones CA, Mollins JE, Pohar S, Beaupre LA. Challenges in Data Synthesis when Examining Long-Term follow-up for Total Knee Replacements. Cochrane Canada Symposium, May, 2015.
    • MacKenzie JR, Werle JR, Powell JN, Marshall DA, Sundaram A, Khong H, Faris PD, Phillips K, Beaupre LA, O'Connor GJ. Five Year Safety and Functional Outcomes of Birmingham Hip Resurfacing. Canadian Orthopaedic Association Annual Meeting, June, 2013.

     

    Presentations and Workshops:

    • The 7th Annual Karin Greaves Memorial Education Seminar: Infection following Total Joint Arthroplasty: full day session for Rehabilitation Professionals offered at UAH campus as well as by Telehealth and remote webinar (L Beaupre, Host and Co-organizer with CA Jones), Edmonton, Canada, November, 2015.
    • The 6th Annual Karin Greaves Memorial Education Seminar: Rehabilitation for Bariatric Patients Undergoing TKA full day session for Rehabilitation Professionals offered at UAH campus as well as by Telehealth and remote webinar (L Beaupre, Host and Co-organizer with CA Jones), Edmonton, Canada, November, 2014.
    • Living with Osteoarthritis. Beaupre LA, Jones CA, Edmonton Wood Forum for OA, October, 2013.