Research
The research interests of the faculty members encompass not only the traditional areas of analytical, inorganic, organic and physical chemistry but also cover many interdisciplinary areas including bioanalytical, bioorganic, biophysical and medicinal chemistry, chemical biology, chemical physics, combinatorial chemistry, environmental chemistry, glycoscience, materials science, nanotechnology, organometallic chemistry and catalysis, surface science, and theoretical and computational chemistry.
Faculty members of the department are involved in academic and industrial collaborations at the national and international levels, with colleagues from foreign countries, including France, Germany, Japan, Mexico, the United Kingdom, and the United States.
On this page, you can read a little about the research interests of our faculty members, including:
- Analytical Chemistry
- Chemical Biology
- Chemical Physics
- Green Chemistry
- Inorganic Chemistry
- Materials and Surfaces
- Nanotechnology
- Organic Chemistry
- Physical Chemistry
- Theoretical and Computational Chemistry
- Research Centre on Nanotechnology
Analytical Chemistry
The analytical chemistry program is among the strongest in North America with a dozen faculty members conducting award-winning research at the forefront of some of the most exciting and significant areas of analytical chemistry.
Much of the recent research is aimed at advancing the state-of-the-art in analytical instrumentation and techniques through increased understanding of the fundamental principles involved. Students graduating from this program readily find employment in government, industry, and academia in fields such as industrial chemicals, high tech, and pharmaceuticals.
Analytical chemistry research at the U of A encompasses a broad range of areas including:
absorption, fluorescence, and Raman spectroscopy; |
analytical instrument design; |
atmospheric chemistry; |
biosensors; |
capillary electrophoresis; |
chemical microinstrumentation or "lab-on-a-chip"; |
chemometrics; |
electroanalytical chemistry; |
electrospray ionization mass spectrometry; |
environmental chemistry and chemical toxicology; |
high sensitivity bioanalytical techniques; |
interfacial chemistry; |
liquid chromatography; |
MALDI MS; |
microarray development; |
molecular electronics; |
multi-dimensional gas chromatography; |
nanoparticle enhanced detection; |
nanoscience; |
polymer brush synthesis and characterization; |
proteomics, genomics, and metabolomics; |
scanning probe microscopy; |
surface enhanced Raman spectroscopy; |
and surface plasmon resonance spectroscopy. |
Chemical Biology
Chemical biology research involves the use of chemical tools to gain a deeper understanding of biological systems. Chemical biologists use a range of technologies and techniques including: chemical synthesis, spectroscopy, imaging, mass spectrometry, molecular biology, enzymology, protein chemistry, biophysical chemistry, and cell biology to study biological systems. They are also often creating new technologies or build tools that may have broad applicability in the biological sciences.
Chemical biology research goals include:
Controlling the function of proteins, cells, or multicellular organisms with small molecules |
Deciphering and manipulating biosynthetic pathways for the production of medically important small molecules |
Chemical modification of biomolecules |
Engineering of biomolecules to give them properties not found in nature |
Coming to a deeper understanding of the chemical basis of life. |
Chemical Physics
Chemical physics encompasses both experimental and theoretical/computational research at the boundaries of chemistry and physics, with a stronger focus on the fundamental physics than in the traditional area of physical chemistry.
Some active projects include studies in:
laser control of quantum dynamics |
excited state molecular dynamics |
rotational spectroscopy |
high resolution and ab initio spectroscopy |
spectroscopy of chiral recognition and absolute configuration of carbohydrates |
helium nanodroplet spectroscopy |
condensed phase linear and non-linear spectroscopy |
Green Chemistry
Green chemistry is an emerging research area of vital importance.
Society is now required to deal with a diminishing supply of nonrenewable fossil fuels and the negative environmental impact of our current methods for producing energy, commodity chemicals, and pharmaceuticals.
As an inherently cross-disciplinary field, green chemistry requires new research and training structures built upon collaborations between disparate fields of science, engineering, economics, and policy. Several faculty members are involved in crucial research projects that aim to address these global challenges.
These faculty members, along with their graduate students, are gaining the required expertise to play a key role in improving chemical efficiency and sustainability in Canada and throughout the world.
Inorganic Chemistry
Inorganic chemistry is an exciting and expanding field of research that encompasses a wide range of areas and is at the crossroads of interdisciplinary inquiry. This is exemplified by work in inorganic/materials chemistry and main group/organometallic chemistry, which are major strengths in the division.
Materials and Surfaces
Research in materials and surfaces explores the properties of matter and the interfaces of their different states. This field highly interdisciplinary and an exciting area for the department.
In collaboration, the faculty is working to develop novel materials with never before observed physical and chemical properties to solve some of the most important problems in health, energy, and the environment. The materials being developed range from "hard" inorganic materials to "soft" organic/polymer-based materials on macro to nano dimensions.
Nanotechnology
Research in nanotechnology is interdisciplinary and diverse, with applications in several fields including chemistry, medicine and microfabrication. Our researchers are at the forefront of this new and exciting science, with many holding appointments with the prestigious Nanotechnology Research Centre (formerly NINT).
Some active projects include:
nanoparticle synthesis and derivatization |
nanoscale structures for solar energy |
self-assembly to build sub-50 nm features on silicon |
asymmetric nanoparticle functionalization (Janus particles) |
adaptive nanotubular architectures |
nanoparticle enhanced spectroscopy |
green nanomaterials |
Organic Chemistry
Drawing upon the experience and knowledge of a large internationally recognized faculty, students studying organic chemistry at the U of A receive an enriching and high quality education. Graduates of our program find successful and fulfilling careers in industry, government and within academia.
Research in organic chemistry in the department covers a wide variety of topics, including:
antimicrobial agents and biological/biochemical mechanisms |
catalysis and organometallic mechanisms |
molecular recognition and supramolecular chemistry |
carbohydrate/protein interactions and biophysical chemistry |
synthesis of biologically active carbohydrates and their libraries |
synthetic methodology and construction of natural products |
antitumor agents and DNA interactions |
new organic materials |
combinatorial synthesis and bioorganic chemistry |
Physical Chemistry
Research in physical chemistry in the department covers a diverse range of topics, including dynamics across time and lengths scale, weakly interacting systems, biophysical chemistry, technique development, and condensed phase studies.
Some active projects include studies in:
laser control |
excited state molecular dynamics |
excited state structural dynamics |
rotational spectroscopy |
high resolution and ab initio spectroscopy |
nucleic acid damage and repair |
photochemistry of fluorescent proteins |
spectroscopy of chiral recognition and absolute configuration of carbohydrates |
helium nanodroplet spectroscopy |
condensed phase spectroscopy |
vibrational circular dichroism spectroscopy of chiral molecules in solution and in thin film |
solid-state nuclear magnetic resonance (NMR) spectroscopy |
Theoretical and Computational Chemistry
Theoretical chemistry utilizes mathematical techniques, and their subsequent numerical and computational implementation, to examine and understand physical and chemical phenomena in a wide range of problems in chemistry.
Research in theoretical and computational chemistry in the department covers a wide variety of topics, some of which include:
Laser control using the multi-configuration time-dependent Hartree (MCTDH) technique |
Excited state molecular dynamics |
Mixed quantum-classical approaches to modelling linear and multidimensional non-linear spectra of condensed phase systems |
Development and applications of model core potentials for studying large molecules or those containing heavy elements |
Quantum mechanical/molecular mechanical (QM/MM) methods for modelling anti-cancer drugs and fluorescent proteins |
Centres and Institutes
In addition to national and international collaborations with industry, the Department of Chemistry houses centres and institutes that produce innovating and exciting research.